Embodiments of the present invention address deficiencies of the art in respect to instant messaging and provide a novel and non-obvious method, system and computer program product for managing e-mail user confidentiality. In one embodiment of the invention, a method for managing e-mail user confidentiality can be provided. The method can include transmitting an e-mail message for delivery to multiple e-mail users and corresponding e-mail addresses, identifying a privacy preference for a particular one of the e-mail users; and, concealing a display within the e-mail message of an e-mail address associated with the particular one of the e-mail users responsive to the privacy preference.